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A list of all the posts and pages found on the site. For you robots out there is an XML version available for digesting as well.
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Posts
Blog Post number 1
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publications
What do we know about spatial navigation, and what else could model-based fMRI tell us?
Published in The Einstein Journal of Biology and Medicine, 2013
You can read the paper here.
Recommended citation: Tyson, A. L. (2013). "What do we know about spatial navigation, and what else could model-based fMRI tell us?" Einstein J. Biol. Med. v29 p32.
Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy
Published in International Journal of Pharmaceutics, 2015
You can read the paper heres.
Recommended citation: Tyson, A. L., Hilton, S. T., Andreae, L. C. (2015). "Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy" Int. J. Pharma. v494 p651.
Decreased functional connectivity within a language subnetwork in benign epilepsy with centrotemporal spikes
Published in Epilepsia Open, 2017
You can read the paper here.
Recommended citation: McGinnity, C. J., Smith, A. B., Yaakub, S. N., Gerbase, S. W., Gammerman, A., Tyson, A. L., Bell, T. K., Elmasri, M., Barker G. J., Richardson, M. P., Pal, D. K. (2017). "Decreased functional connectivity within a language subnetwork in benign epilepsy with centrotemporal spikes" Epilepsia Open v494 p651.
The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice
Published in Molecular Autism, 2019
You can read the paper here.
Recommended citation: Pervolaraki, E.*, Tyson, A. L.*, Pibiri, F., Poulter, S. L., Reichelt, A. C., Rodgers, R. J., Clapcote, S. J., Lever, C., Andreae, L. C.*, Dachtler, J.* (2019). "The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice" Mol. Autism v10 p8.
Optimisation and validation of hydrogel-based brain tissue clearing shows uniform expansion across anatomical regions and spatial scales
Published in Scientific Reports, 2019
You can read the paper here.
Recommended citation: Tyson, A. L., Akhtar, A., Andreae, L. C. (2019). "Optimisation and validation of hydrogel-based brain tissue clearing shows uniform expansion across anatomical regions and spatial scales" Sci. Rep. v9 #12084.
Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint
Published in Journal of Cell Biology, 2020
You can read the paper here and find the image analysis software here.
Recommended citation: Jackman, M.*, Marcozzi, C.*, Barbiero, M., Pardo, M., Yu, L., Tyson, A. L., Choudray, J., Pines, J. (2020). "Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint" J. Cell Biol. v219(6)
Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
Published in Cell, 2020
You can read the paper here and find the software for:
- Quantification of proximity ligation assay images here.
- Quantification of acini images here.
- Quantification of calcium flux here.
Recommended citation: Koundouros, N., Karali, E., Tripp, A., Valle, A., Inglese, P., Perry, N. J. S, Magee, D. J., Virmouni, S. A., Elder, G. A., Tyson, A. L., Luisa Doria, M., van Weverwijk, A., Soares, R. F., Isacke, C. M., Nicholson, J. K., Glen, R. C., Takats, Z., Poulogiannis, G. (2020) "Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids" Cell v181 p1
BrainGlobe Atlas API: a common interface for neuroanatomical atlases
Published in Journal of Open Source Software, 2020
You can read the paper here and find the software here.
Recommended citation: Claudi, F.*, Petrucco, L.*, Tyson, A. L.*, Branco, T., Margrie, T. W., Portugues, R. (2020) "BrainGlobe Atlas API: a common interface for neuroanatomical atlases" Journal of Open Source Software, 5(54), 2668
Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1
Published in Scientific Reports, 2021
You can read the paper here.
Recommended citation: Brown, A. P. Y.*, Cossell, L.*, Strom, M., Tyson, A. L., Vélez-Fort, M., Margrie, T.W. (2021). "Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1" Sci. Rep. v11 #4983.
Visualizing anatomically registered data with Brainrender
Published in eLife, 2021
You can read the paper at eLife or try brainrender here.
Recommended citation: Claudi, F., Tyson, A. L., Petrucco, L., Margrie, T.W., Portugues, R., Branco, T. (2021). "Visualizing anatomically registered data with Brainrender" eLife 2021;10:e65751
A deep learning algorithm for 3D cell detection in whole mouse brain image datasets
Published in PLoS Computational Biology, 2021
You can read the paper at PLoS Computational Biology or try the software here.
Recommended citation: Tyson, A. L.*, Rousseau, C. V.*, Niedworok, C. J.*, Keshavarzi, S., Tsitoura, C., Cossell, L., Strom, M., Margrie, T. W. (2021). "A deep learning algorithm for 3D cell detection in whole mouse brain image datasets" PLoS Comp Bio 17(5): e1009074.
Mesoscale microscopy and image analysis tools for understanding the brain
Published in Progress in Biophysics and Molecular Biology, 2022
You can read the paper here.
Recommended citation: Tyson, A. L., Margrie, T. W. (2022). "Mesoscale microscopy and image analysis tools for understanding the brain" Progress in Biophysics and Molecular Biology v168 p81
Accurate determination of marker location within whole-brain microscopy images
Published in Scientific Reports, 2022
You can read the paper at Scientific Reports or try the software here.
Recommended citation: Tyson, A. L.*, Vélez-Fort, M.*, Rousseau, C. V.*, Cossell, L., Tsitoura, C., Lenzi, S. C., Obenhaus, H. A., Claudi, F., Branco, T., Margrie, T. W. (2022). "Accurate determination of marker location within whole-brain microscopy images" Scientific Reports
3D single-cell shape analysis of cancer cells using geometric deep learning
Published in bioRxiv, 2022
You can read the paper here.
Recommended citation: De Vries, M., Dent, L., Curry, N., Rowe-Browen, L., Tyson, A., Dunsby, C., Bakal, C. (2022). "3D single-cell shape analysis of cancer cells using geometric deep learning" bioRxiv
Multisensory coding of angular head velocity in the retrosplenial cortex
Published in Neuron, 2022
You can read the paper here.
Recommended citation: Keshavarzi, S., Bracey, E. F., Faville, R. A., Campagner, D., Tyson, A. L., Lenzi, S. C., Branco, T., Margrie, T. W. (2022). "Multisensory coding of angular head velocity in the retrosplenial cortex" Neuron v110(3), p532
software
talks
teaching
Introduction to Image Analysis in FIJI
Technical course, Institute of Cancer Research, 2018
Introduction to fundamental image analysis using FIJI for students & staff, taught at the Institute of Cancer Research, London, U.K. Slides and course materials can be found here.
Introduction to Python Programming
Technical course, Institute of Cancer Research, 2021
Introduction to Python programming course series for students & staff, taught at the Institute of Cancer Research, London, U.K. Courses included:
SWC/GCNU Software Skills
Technical course, Sainsbury Wellcome Centre, 2023
Ongoing Python programming and general software skills training courses taught at the Sainsbury Wellcome Centre, UCL, U.K. All materials can be found here.